GL1X · GenesisL1 explorer

Ligand · R8J

R8J · 6-(5-oxo-4-(1H-1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid

R8J, 6-(5-oxo-4-(1H-1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinic acid (C11 H8 N6 O3, 272.2 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
R8J
Formula
C11 H8 N6 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

R8J in 2 structures; the first of them:

  • 5A3U · HIF prolyl hydroxylase 2 (PHD2/EGLN1) in complex with 6-(5-oxo-4-(1H… · R8J A1421 · binds MET299, TYR303, HIS313, ASP315, ARG322, TYR329, HIS374, VAL376 and 3 more
  • 5A3U · Hif prolyl hydroxylase 2 (PHD2/EGLN1) in complex with 6-(5-oxo-4-(1H… · R8J A1421 · binds MET299, TYR303, HIS313, ASP315, ARG322, TYR329, HIS374, VAL376 and 3 more

Residues it binds most

ARG 6, HIS 6, TYR 6, ASP 6, MET 6, TRP 6, VAL 6, ILE 4, LEU 2, ASN 2 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.