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Ligand · R49

R49 · 1-{4-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea

R49, 1-{4-[(6-aminoquinolin-4-yl)amino]phenyl}-3-[3-tert-butyl-1-(3-methylphenyl)-1H-pyrazol-5-yl]urea (C30 H31 N7 O, 505.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
R49
Formula
C30 H31 N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

R49 in 2 structures; the first of them:

  • 3HV3 · Human p38 MAP Kinase in Complex with RL49 · R49 A361 · binds VAL30, VAL38, ALA51, LYS53, ARG67, ARG70, GLU71, LEU74 and 16 more
  • 3HV3 · Human P38 MAP kinase in complex with RL49 · R49 A361 · binds VAL30, VAL38, ALA51, LYS53, ARG67, ARG70, GLU71, LEU74 and 16 more

Residues it binds most

ILE 2, LEU 2, VAL 2, ARG 2, HIS 2, MET 2, ALA 2, ASP 2, GLU 2, GLY 2 (residue and the binding sites it lines).

Found with

  • BOG · octyl beta-D-glucopyranoside
  • GOL · Glycerol

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