Ligand · R05

R05 · 5-(2-azanylpyridin-4-yl)-~{N}-[[2,6-bis(fluoranyl) phenyl]methyl]-2-methyl-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine

R05, 5-(2-azanylpyridin-4-yl)-~{N}-[[2,6-bis(fluoranyl) phenyl]methyl]-2-methyl-7~{H}-pyrrolo[2,3-d]pyrimidin-4-amine (C19 H16 F2 N6, 366.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component: R05
Formula: C19 H16 F2 N6
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

R05 in 2 structures; the first of them:

7A5N · Structure of DYRK1A in complex with compound 34 · R05 A501 · binds ILE165, GLY166, LYS167, GLY168, PHE170, VAL173, ALA186, LYS188 and 11 more
7A5N · Structure of DYRK1A in complex with compound 34 · R05 A501 · binds ILE165, GLY166, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203 and 8 more

Residues it binds most

VAL 4, GLU 4, PHE 4, LEU 4, LYS 4, GLY 4, ALA 4, ASP 4, ILE 4, SER 4 (residue and the binding sites it lines).

Found with

CL · Chloride ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.