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Ligand · QZW

QZW · 4-[2-methyl-4-(thiophen-3-ylmethoxy)-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]pyridin-2-amine

QZW, 4-[2-methyl-4-(thiophen-3-ylmethoxy)-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]pyridin-2-amine (C17 H15 N5 O S, 337.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
QZW
Formula
C17 H15 N5 O S
Class
ligand
Structures
2
PDB entries
1

Binding sites

QZW in 2 structures; the first of them:

  • 7A5L · tructure of DYRK1A in complex with compound 24 · QZW A501 · binds ILE165, GLY166, LYS167, GLY168, PHE170, VAL173, ALA186, LYS188 and 11 more
  • 7A5L · Tructure of DYRK1A in complex with compound 24 · QZW A501 · binds ILE165, GLY166, LYS167, GLY168, PHE170, VAL173, ALA186, LYS188 and 11 more

Residues it binds most

PHE 2, VAL 2, GLU 2, GLY 2, LEU 2, LYS 2, ALA 2, ASP 2, ILE 2, MET 2 (residue and the binding sites it lines).

Found with

  • CL · Chloride ion

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