Ligand · QWZ
QWZ · 1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl) ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one
QWZ, 1-cycloheptyl-3-{4-methoxy-3-[2-(4-methoxyphenyl) ethoxy]phenyl}-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one (C28 H36 N2 O4, 464.6 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site…
- Component
- QWZ
- Formula
- C28 H36 N2 O4
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
QWZ in 4 structures; the first of them:
- 7A2F · Crystal structure of T. brucei PDE-B1 catalytic domain with inhibitor NPD-656 · QWZ B1007 · binds TYR668, HIS669, MET785, ILE823, ASN825, TRP836, ALA837, VAL840 and 6 more
- 7AB9 · Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-656 · QWZ A512 · binds TYR159, HIS160, MET273, LEU319, ASN321, TYR329, TRP332, THR333 and 9 more
- 7A2F · Crystal structure of T. brucei pde-B1 catalytic domain with inhibitor npd-656 · QWZ B1007 · binds MET785, ILE823, ASN825, ALA837, VAL840, PHE844, MET861, GLY873 and 2 more
- 7AB9 · Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor npd-656 · QWZ A512 · binds TYR159, HIS160, MET273, LEU319, ASN321, THR333, ILE336, MET357 and 4 more
Residues it binds most
MET 10, PHE 10, TYR 8, ILE 10, ASN 10, GLN 10, HIS 9, LEU 8, SER 8, THR 8 (residue and the binding sites it lines).
Found with
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