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Ligand · QVB

QVB · 5-chloranyl-6-fluoranyl-3-(2-propan-2-yloxyphenyl)-1~{H}-indole-2-carboxamide

QVB, 5-chloranyl-6-fluoranyl-3-(2-propan-2-yloxyphenyl)-1~{H}-indole-2-carboxamide (C18 H16 Cl F N2 O2, 346.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
QVB
Formula
C18 H16 Cl F N2 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

QVB in 2 structures; the first of them:

  • 7A14 · Crystal structure of human methionine aminopeptidase-2 in complex with an inhibitor… · QVB A508 · binds PHE219, PRO220, HIS231, ASP262, LEU328, HIS331, ILE338, HIS339 and 8 more
  • 7A14 · Crystal structure of human methionine aminopeptidase-2 in complex with an inhibitor… · QVB A508 · binds PHE219, PRO220, HIS231, ASP262, LEU328, HIS331, ILE338, HIS339 and 7 more

Residues it binds most

HIS 2, LEU 2, TYR 2, GLU 2, ALA 2, ASP 2, ILE 2, MET 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • MN · Manganese (II) ion
  • PO4 · Phosphate ion

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