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Ligand · QNK

QNK · 6-[(6~{S},8~{R})-7-[(1-fluoranylcyclopropyl)methyl]-8-methyl-2,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]-~{N}-[1-(3-fluoranylpropyl)azetidin-3-yl]pyridin-3-amine

QNK, 6-[(6~{S},8~{R})-7-[(1-fluoranylcyclopropyl)methyl]-8-methyl-2,6,8,9-tetrahydropyrazolo[4,3-f]isoquinolin-6-yl]-~{N}-[1-(3-fluoranylpropyl)azetidin-3-yl]pyridin-3-amine (C26 H32 F2 N6, 466.6 g/mol), in the MolNFT structures on…

Component
QNK
Formula
C26 H32 F2 N6
Class
ligand
Structures
2
PDB entries
1

Binding sites

QNK in 2 structures; the first of them:

  • 6ZOS · Oestrogen receptor ligand binding domain in complex with compound 18 · QNK A601 · binds MET343, LEU346, THR347, LEU349, ALA350, ASP351, GLU353, LEU354 and 18 more
  • 6ZOS · Oestrogen receptor ligand binding domain in complex with compound 18 · QNK A601 · binds MET343, LEU346, THR347, LEU349, ALA350, ASP351, GLU353, LEU354 and 18 more

Residues it binds most

LEU 4, MET 4, VAL 4, ALA 4, ARG 4, ASN 4, ASP 4, GLU 4, GLY 4, HIS 4 (residue and the binding sites it lines).

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