Ligand · QKA

QKA · (1R,2R)-2-[(4ar,7ar)-2-amino-6-(pyrimidin-2-yl)-4A,5,6, 7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7A(4H)-yl]-N-{[(1R,2R)-2-methylcyclopropyl]methyl}cyclopropane-1-carboxamide

QKA, (1R,2R)-2-[(4ar,7ar)-2-amino-6-(pyrimidin-2-yl)-4A,5,6, 7-tetrahydropyrrolo[3,4-d][1,3]thiazin-7A(4H)-yl]-N-{[(1R,2R)-2-methylcyclopropyl]methyl}cyclopropane-1-carboxamide (C19 H26 N6 O S, 386.5 g/mol), in the MolNFT structures on…

Component: QKA
Formula: C19 H26 N6 O S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

QKA in 2 structures; the first of them:

6UWP · BACE-1 in complex with compound #32 · QKA A401 · binds SER10, GLY11, GLN12, GLY13, LEU30, ASP32, GLY34, SER35 and 13 more
6UWP · Bace-1 in complex with compound #32 · QKA A401 · binds SER10, GLY11, GLN12, GLY13, LEU30, ASP32, GLY34, SER35 and 12 more

Residues it binds most

GLY 4, SER 4, ASP 4, ILE 4, THR 4, TRP 4, ARG 4, GLN 4, LEU 4, TYR 4 (residue and the binding sites it lines).

Found with

SO4 · Sulfate ion
GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.