Ligand · QJM

QJM · N-{(1R,2R)-2-[(4as,7ar)-2-amino-4A,5-dihydro-4H-furo[3, 4-d][1,3]thiazin-7A(7H)-yl]cyclopropyl}-5-fluoropyridine-2-carboxamide

QJM, N-{(1R,2R)-2-[(4as,7ar)-2-amino-4A,5-dihydro-4H-furo[3, 4-d][1,3]thiazin-7A(7H)-yl]cyclopropyl}-5-fluoropyridine-2-carboxamide (C15 H17 F N4 O2 S, 336.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component: QJM
Formula: C15 H17 F N4 O2 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

QJM in 2 structures; the first of them:

6UVP · BACE-1 in complex with compound #3 · QJM A402 · binds HIS362, ASP363, GLU364, PHE365, ARG366, THR367, GLN55
6UVP · Bace-1 in complex with compound #3 · QJM A402 · binds HIS362, ASP363, GLU364, PHE365, ARG366, THR367, GLN55

Residues it binds most

ARG 4, ASP 4, GLU 4, HIS 4, PHE 4, THR 4, GLN 2 (residue and the binding sites it lines).

Found with

QJJ · N-{(1S,2S)-2-[(4as,7ar)-2-amino-4A,5-dihydro-4H-furo[3, 4-d][1,3]thiazin-7A(7H)-yl]cyclopropyl}-5-fluoropyridine-2-carboxamide
SO4 · Sulfate ion
GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.