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Ligand · QJ5

QJ5 · 5-cyclopropyl-1-[3-[(4-propylphenyl) sulfonylamino]phenyl]pyrazole-4-carboxylic acid

QJ5, 5-cyclopropyl-1-[3-[(4-propylphenyl) sulfonylamino]phenyl]pyrazole-4-carboxylic acid (C22 H23 N3 O4 S, 425.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within…

Component
QJ5
Formula
C22 H23 N3 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

QJ5 in 2 structures; the first of them:

  • 6ZF2 · Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein… · QJ5 A706 · binds TYR334, SER363, GLY364, ARG415, ILE461, GLY462, PHE478, ARG483 and 9 more
  • 6ZF2 · KEAP1 kelch domain bound to a small molecule inhibitor of the KEAP1- NRF2 protein-protein… · QJ5 A706 · binds TYR334, SER363, GLY364, ARG415, ILE461, GLY462, PHE478, ARG483 and 9 more

Residues it binds most

GLY 2, SER 2, TYR 2, ARG 2, PHE 2, ALA 2, ILE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

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