GL1X · GenesisL1 explorer

Ligand · QHT

QHT · 5-cyclopropyl-1-[3-[(2,3,5,6-tetramethylphenyl) sulfonylamino]phenyl]pyrazole-4-carboxylic acid

QHT, 5-cyclopropyl-1-[3-[(2,3,5,6-tetramethylphenyl) sulfonylamino]phenyl]pyrazole-4-carboxylic acid (C23 H25 N3 O4 S, 439.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
QHT
Formula
C23 H25 N3 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

QHT in 2 structures; the first of them:

  • 6ZF0 · Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein… · QHT A712 · binds TYR334, SER363, GLY364, ASN382, ARG415, ILE461, GLY462, PHE478 and 10 more
  • 6ZF0 · KEAP1 kelch domain bound to a small molecule inhibitor of the KEAP1- NRF2 protein-protein… · QHT A712 · binds TYR334, SER363, GLY364, ASN382, ARG415, ILE461, GLY462, PHE478 and 10 more

Residues it binds most

GLY 2, SER 2, TYR 2, ARG 2, PHE 2, ALA 2, ASN 2, ILE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.