GL1X · GenesisL1 explorer

Ligand · QHQ

QHQ · 5-cyclopropyl-1-[3-[2-hydroxy-2-oxoethyl-(3-methoxyphenyl)sulfonyl-amino]phenyl]pyrazole-4-carboxylic acid

QHQ, 5-cyclopropyl-1-[3-[2-hydroxy-2-oxoethyl-(3-methoxyphenyl)sulfonyl-amino]phenyl]pyrazole-4-carboxylic acid (C22 H21 N3 O7 S, 471.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site…

Component
QHQ
Formula
C22 H21 N3 O7 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

QHQ in 2 structures; the first of them:

  • 6ZF7 · Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein… · QHQ A718 · binds TYR334, SER363, GLY364, ARG380, ASN414, ARG415, ILE461, GLY462 and 11 more
  • 6ZF7 · KEAP1 kelch domain bound to a small molecule inhibitor of the KEAP1- NRF2 protein-protein… · QHQ A718 · binds TYR334, SER363, GLY364, ARG380, ASN414, ARG415, ILE461, GLY462 and 11 more

Residues it binds most

GLY 2, SER 2, ARG 2, TYR 2, PHE 2, ALA 2, ASN 2, ILE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.