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Ligand · QH5

QH5 · ~{N}-[3-[5-cyclopropyl-4-(2~{H}-1,2,3,4-tetrazol-5-yl) pyrazol-1-yl]phenyl]benzenesulfonamide

QH5, ~{N}-[3-[5-cyclopropyl-4-(2~{H}-1,2,3,4-tetrazol-5-yl) pyrazol-1-yl]phenyl]benzenesulfonamide (C19 H17 N7 O2 S, 407.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
QH5
Formula
C19 H17 N7 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

QH5 in 2 structures; the first of them:

  • 6ZF3 · Keap1 kelch domain bound to a small molecule inhibitor of the Keap1-Nrf2 protein-protein… · QH5 A1101 · binds TYR334, SER363, GLY364, ASN382, ARG415, ILE461, GLY462, PHE478 and 10 more
  • 6ZF3 · KEAP1 kelch domain bound to a small molecule inhibitor of the KEAP1- NRF2 protein-protein… · QH5 A1101 · binds TYR334, SER363, GLY364, ASN382, ARG415, ILE461, GLY462, PHE478 and 10 more

Residues it binds most

GLY 2, SER 2, TYR 2, ARG 2, PHE 2, ALA 2, ASN 2, ILE 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

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