Ligand · QFO

QFO · (3S,4R)-3-fluoro-1-(4-{[8-{3-[(methanesulfonyl) methyl]azetidin-1-yl}-5-(propan-2-yl)-2,7-naphthyridin-3-yl]amino}pyrimidin-2-yl)-3-methylpiperidin-4-ol

QFO, (3S,4R)-3-fluoro-1-(4-{[8-{3-[(methanesulfonyl) methyl]azetidin-1-yl}-5-(propan-2-yl)-2,7-naphthyridin-3-yl]amino}pyrimidin-2-yl)-3-methylpiperidin-4-ol (C26 H34 F N7 O3 S, 543.7 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component: QFO
Formula: C26 H34 F N7 O3 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

QFO in 2 structures; the first of them:

8D76 · Crystal Structure of EGFR LRTM with compound 24 · QFO A1504 · binds LYS716, LEU718, GLY719, PHE723, VAL726, LYS728, ALA743, LYS745 and 15 more
8D76 · Crystal structure of EGFR lrtm with compound 24 · QFO A1504 · binds LYS716, LEU718, GLY719, PHE723, VAL726, LYS728, ALA743, LYS745 and 15 more

Residues it binds most

MET 4, LEU 4, LYS 4, ASP 4, GLY 4, ALA 4, CYS 4, GLN 4, GLU 4, PHE 4 (residue and the binding sites it lines).

Found with

GOL · Glycerol

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