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Ligand · QFB

QFB · 7-[[4-[4-[[(3~{R},4~{R})-3-azanyloxan-4-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{N},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide

QFB, 7-[[4-[4-[[(3~{R},4~{R})-3-azanyloxan-4-yl]amino]pyrazol-1-yl]pyrimidin-2-yl]amino]-~{N},3-dimethyl-imidazo[1,5-a]pyridine-1-carboxamide (C22 H26 N10 O2, 462.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB…

Component
QFB
Formula
C22 H26 N10 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

QFB in 1 structure; the first of them:

  • 6ZCQ · SYK Kinase domain in complex with diamine inhibitor 5 · QFB A701 · binds LEU377, GLY378, SER379, GLY380, PHE382, VAL385, ALA400, LYS402 and 13 more
  • 6ZCQ · Syk kinase domain in complex with diamine inhibitor 5 · QFB A701 · binds LEU377, GLY378, SER379, GLY380, PHE382, VAL385, ALA400, LYS402 and 12 more

Residues it binds most

GLY 2, ALA 2, GLU 2, LEU 2, MET 2, SER 2, VAL 2, ARG 2, ASN 2, ASP 2 (residue and the binding sites it lines).

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