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Ligand · Q12

Q12 · 7-(3,4-dimethoxyphenyl)-6-methylquinazoline-2,4-diamine

Q12, 7-(3,4-dimethoxyphenyl)-6-methylquinazoline-2,4-diamine (C17 H18 N4 O2, 310.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds…

Component
Q12
Formula
C17 H18 N4 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

Q12 in 2 structures; the first of them:

  • 3SR5 · S. aureus Dihydrofolate Reductase complexed with novel 7-aryl-2,4-diaminoquinazolines · Q12 X169 · binds LEU6, VAL7, ALA8, LEU21, ASP28, LEU29, VAL32, THR47 and 5 more
  • 3SR5 · S. aureus dihydrofolate reductase complexed with novel 7-aryl-2,4- diaminoquinazolines · Q12 X169 · binds LEU6, VAL7, ALA8, LEU21, ASP28, LEU29, VAL32, THR47 and 5 more

Residues it binds most

LEU 2, PHE 2, THR 2, VAL 2, ALA 2, ASP 2, ILE 2 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate

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