Ligand · PZ1
PZ1 · (6R)-6-({[1-(3-hydroxypropyl)-1,7-dihydroquinolin-7-yl]oxy}methyl)-1-(4-{3-[(2-methoxybenzyl)oxy]propoxy}phenyl)piperazin-2-one
PZ1, (6R)-6-({[1-(3-hydroxypropyl)-1,7-dihydroquinolin-7-yl]oxy}methyl)-1-(4-{3-[(2-methoxybenzyl)oxy]propoxy}phenyl)piperazin-2-one (C34 H41 N3 O6, 587.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries).…
- Component
- PZ1
- Formula
- C34 H41 N3 O6
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
PZ1 in 4 structures; the first of them:
- 2BKS · crystal structure of Renin-PF00074777 complex · PZ1 B401 · binds THR13, GLN14, TYR15, VAL31, ASP33, GLY35, SER36, TRP40 and 20 more
- 2FS4 · Ketopiperazine-Based Renin Inhibitors: Optimization of the C ring · PZ1 B805 · binds THR13, GLN14, TYR15, VAL31, ASP33, GLY35, SER36, TRP40 and 20 more
- 2BKS · Crystal structure of renin-PF00074777 complex · PZ1 B401 · binds THR13, GLN14, TYR15, VAL31, ASP33, GLY35, SER36, TRP40 and 20 more
- 2FS4 · Ketopiperazine-based renin inhibitors: optimization of the C ring · PZ1 B805 · binds THR13, GLN14, TYR15, VAL31, ASP33, GLY35, SER36, TRP40 and 20 more
Residues it binds most
VAL 4, ALA 4, ASP 4, GLY 4, PHE 4, PRO 4, SER 4, THR 4, TYR 4, GLN 4 (residue and the binding sites it lines).
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