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Ligand · PXK

PXK · 6-(4,4-dimethylpent-2-ynyl)-4~{H}-pyrrolo[2,3-d][1,3]thiazole

PXK, 6-(4,4-dimethylpent-2-ynyl)-4~{H}-pyrrolo[2,3-d][1,3]thiazole (C12 H14 N2 S, 218.3 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
PXK
Formula
C12 H14 N2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

PXK in 2 structures; the first of them:

  • 3PXK · FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH Pyrrolo[2,3-d]thiazole · PXK A701 · binds ILE428, GLY429, GLU430, GLY431, VAL436, ALA452, LYS454, VAL484 and 6 more
  • 3PXK · Focal adhesion kinase catalytic domain in complex with PYRROLO[2,3- D]THIAZOLE · PXK A701 · binds ILE428, GLY429, GLU430, GLY431, VAL436, ALA452, LYS454, VAL484 and 6 more

Residues it binds most

GLU 4, GLY 4, LEU 4, VAL 4, ALA 4, CYS 4, ILE 4, LYS 4, MET 4, ARG 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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