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Ligand · PVT

PVT · 5-[[4-(pyridin-3-ylmethylamino)-5-(trifluoromethyl) pyrimidin-2-yl]amino]-1,3-dihydroindol-2-one

PVT, 5-[[4-(pyridin-3-ylmethylamino)-5-(trifluoromethyl) pyrimidin-2-yl]amino]-1,3-dihydroindol-2-one (C19 H15 F3 N6 O, 400.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
PVT
Formula
C19 H15 F3 N6 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

PVT in 2 structures; the first of them:

  • 6YVS · FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH… · PVT A701 · binds ARG426, ILE428, GLY429, VAL436, ALA452, LYS454, VAL484, MET499 and 8 more
  • 6YVS · Focal adhesion kinase catalytic domain in complex with 5-{4-[(pyridin… · PVT A701 · binds ARG426, ILE428, GLY429, VAL436, ALA452, LYS454, VAL484, MET499 and 8 more

Residues it binds most

GLU 8, GLY 8, LEU 8, VAL 8, ALA 8, CYS 8, ILE 8, LYS 8, MET 8, THR 8 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

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