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Ligand · PUC

PUC · (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid

PUC, (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid (C21 H34 O4, 350.5 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its…

Component
PUC
Formula
C21 H34 O4
Class
ligand
Structures
5
PDB entries
4

Binding sites

PUC in 5 structures; the first of them:

  • 7TX8 · Long form D7 protein from Anopheles darlingi with U46619 and serotonin bound · PUC A402 · binds LEU13, TYR16, THR17, GLN20, TRP38, HIS39, TRP41, LEU43 and 11 more
  • 8I4C · Cryo-EM structure of U46619-bound ABCC4 · PUC A1401 · binds PHE211, PHE324, LEU363, LEU367, PHE368, ARG375, THR846, GLY991 and 4 more
  • 8J3Z · Cryo-EM structure of ATP-U46619-bound ABCC4 · PUC A1403 · binds HIS152, PHE156, PHE211, LEU321, PHE324, LEU363, LEU367, PHE368 and 11 more
  • 8XJO · U46619 bound Thromboxane A2 receptor-Gq Protein Complex · PUC R601 · binds SER27, ALA31, PHE34, CYS35, GLY77, LEU78, THR81, GLY82 and 17 more
  • 7TX8 · Long form D7 protein from anopheles darlingi with U46619 and serotonin bound · PUC A402 · binds TYR16, GLN20, TRP38, HIS39, TRP41, LEU43, TYR53, VAL57 and 5 more

Residues it binds most

LEU 11, HIS 10, TYR 8, TRP 11, THR 11, VAL 9, GLY 11, GLN 11, PHE 3, LYS 8 (residue and the binding sites it lines).

Found with

  • SRO · Serotonin
  • ATP · Adenosine-5'-triphosphate
  • MG · Magnesium ion

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