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Ligand · PRZ

PRZ · 2-isobutyl-3-methoxypyrazine

PRZ, 2-isobutyl-3-methoxypyrazine (C9 H14 N2 O, 166.2 g/mol), in the MolNFT structures on GenesisL1: bound in 14 records (7 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
PRZ
Formula
C9 H14 N2 O
Class
ligand
Structures
14
PDB entries
7

Binding sites

PRZ in 14 structures; the first of them:

  • 1DZK · Porcine Odorant Binding Protein Complexed with pyrazine (2-isobutyl-3-metoxypyrazine) · PRZ A700 · binds PHE35, VAL37, MET39, VAL80, ASN86, PHE88, ASN102, MET114 and 2 more
  • 1GT1 · Complex of Bovine Odorant Binding Protein with Aminoanthracene and pyrazine · PRZ A1160 · binds ILE22, PHE36, THR38, PHE40, PHE54, PHE56, TYR83, PHE89 and 7 more
  • 1HQP · Crystal structure of a truncated form of porcine odorant-binding protein · PRZ A160 · binds PHE35, VAL37, MET39, LEU53, PHE55, LEU68, VAL80, ASN86 and 4 more
  • 1QY1 · Thermodynamics of Binding of 2-methoxy-3-isopropylpyrazine and… · PRZ A300 · binds LEU24, PHE38, LEU40, PHE56, MET69, TYR84, PHE90, ALA103 and 3 more
  • 1YP6 · Van der Waals Interactions Dominate Hydrophobic Association in a Protein Binding Site… · PRZ A203 · binds LEU40, LEU42, LEU54, PHE56, PHE90, ILE92, LEU101, ALA103 and 5 more
  • 2NND · The Structural Identification of the Interaction Site and Functional State of RBP for its… · PRZ A300 · binds LEU24, PHE38, LEU40, LEU42, LEU54, PHE56, MET73, TYR88 and 5 more
  • 2P70 · Bombyx mori pheromone binding protein bound to bell pepper odorant · PRZ A2961 · binds PHE12, ILE52, SER56, MET61, LEU62, LEU68, VAL94, THR111 and 3 more
  • 1DZK · Porcine odorant binding protein complexed with pyrazine (2-isobutyl-3-metoxypyrazine) · PRZ A700 · binds PHE35, VAL37, MET39, VAL80, ASN86, PHE88, ASN102, MET114 and 2 more
  • 1GT1 · Complex of bovine odorant binding protein with aminoanthracene and pyrazine · PRZ A1160 · binds ILE22, PHE36, THR38, PHE40, PHE54, PHE56, TYR83, PHE89 and 7 more
  • 1HQP · Crystal structure of a truncated form of porcine odorant-binding protein · PRZ A160 · binds PHE35, VAL37, MET39, LEU53, PHE55, LEU68, VAL80, ASN86 and 4 more
  • 1QY1 · Thermodynamics of binding of 2-methoxy-3-isopropylpyrazine and 2… · PRZ A300 · binds LEU24, PHE38, LEU40, PHE56, MET69, TYR84, PHE90, ALA103 and 3 more
  • 1YP6 · Van der waals interactions dominate hydrophobic association in a protein binding site… · PRZ A203 · binds LEU40, LEU42, LEU54, PHE56, PHE90, ILE92, LEU101, ALA103 and 5 more
  • 2NND · The structural identification of the interaction site and functional state of rbp for its… · PRZ A300 · binds LEU24, PHE38, LEU40, LEU42, LEU54, PHE56, MET73, TYR88 and 5 more
  • 2P70 · Bombyx mori pheromone binding protein bound to bell pepper odorant · PRZ A2961 · binds PHE12, ILE52, SER56, MET61, LEU62, LEU68, VAL94, THR111 and 3 more

Residues it binds most

PHE 18, LEU 16, MET 16, VAL 8, ASN 8, ILE 12, ALA 10, THR 8, TYR 6, GLY 6 (residue and the binding sites it lines).

Found with

  • CD · Cadmium ion
  • 3OM · (3S)-1-octen-3-ol
  • ANC · Anthracen-1-ylamine
  • NA · Sodium ion
  • CL · Chloride ion

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