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Ligand · PMF

PMF · Phenylmethylsulfonyl fluoride

PMF, Phenylmethylsulfonyl fluoride (C7 H7 F O2 S, 174.2 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
PMF
Formula
C7 H7 F O2 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

PMF in 3 structures; the first of them:

  • 6MA8 · Human CYP3A4 bound to PMSF · PMF A604 · binds ARG105, SER119, ARG212, ILE301, PHE304, ALA305, ALA370
  • 8GKP · Crystal Structure Analysis of Aspergillus fumigatus alkaline protease · PMF C501 · binds TYR119, LEU120, HIS193, SER255, LEU256, GLY257, ALA281, GLY283 and 4 more
  • 6MA8 · Human CYP3A4 bound to pmsf · PMF A604 · binds ARG105, SER119, ARG212, ILE301, PHE304, ALA305

Residues it binds most

GLY 2, SER 4, ALA 4, ARG 2, LEU 2, ASN 2, HIS 2, ILE 2, PHE 2, THR 2 (residue and the binding sites it lines).

Found with

  • HEM · Protoporphyrin IX containing Fe
  • DMS · Dimethyl sulfoxide
  • EDO · 1,2-ethanediol
  • GOL · Glycerol
  • NA · Sodium ion
  • SO4 · Sulfate ion
  • FMT · Formic acid
  • PEG · Di(hydroxyethyl)ether

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