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Ligand · PHP

PHP · (2-phenyl-1-carbobenzyl-oxyvalyl-amino)-ethyl-phosphinic acid

PHP, (2-phenyl-1-carbobenzyl-oxyvalyl-amino)-ethyl-phosphinic acid (C42 H51 N4 O8 P, 770.9 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
PHP
Formula
C42 H51 N4 O8 P
Class
ligand
Structures
2
PDB entries
1

Binding sites

PHP in 2 structures; the first of them:

  • 1HOS · Inhibition of human immunodeficiency virus-1 protease by a C2-symmetric phosphinate… · PHP A400 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 19 more
  • 1HOS · Inhibition of human immunodeficiency virus-1 protease by a C2- symmetric phosphinate… · PHP A400 · binds LEU23, ASP25, GLY27, ALA28, ASP29, ASP30, VAL32, ILE47 and 19 more

Residues it binds most

GLY 2, ILE 2, ASP 2, VAL 2, ALA 2, LEU 2, PRO 2 (residue and the binding sites it lines).

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