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Ligand · PGX

PGX · 7-[6-(3-hydroperoxy-oct-1-enyl)-2,3-dioxa-bicyclo[2.2.1]hept-5-yl]-hept-5-enoic acid

PGX, 7-[6-(3-hydroperoxy-oct-1-enyl)-2,3-dioxa-bicyclo[2.2.1]hept-5-yl]-hept-5-enoic acid (C20 H32 O6, 368.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5…

Component
PGX
Formula
C20 H32 O6
Class
ligand
Structures
2
PDB entries
1

Binding sites

PGX in 2 structures; the first of them:

  • 1DDX · Crystal structure of a mixture of arachidonic acid and prostaglandin bound to the… · PGX A701 · binds ARG120, PHE205, PHE209, PHE210, VAL228, VAL344, TYR348, VAL349 and 15 more
  • 1DDX · Crystal structure of a mixture of arachidonic acid and prostaglandin bound to the… · PGX A701 · binds ARG120, PHE205, PHE209, PHE210, VAL228, VAL344, TYR348, VAL349 and 15 more

Residues it binds most

PHE 8, VAL 8, LEU 8, TYR 8, GLY 8, SER 8, ALA 8, MET 8, TRP 8, THR 4 (residue and the binding sites it lines).

Found with

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • BOG · octyl beta-D-glucopyranoside

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