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Ligand · PFW

PFW · 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline

PFW, 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(quinolin-2-yl)ethoxy]quinazoline (C31 H30 N4 O2, 490.6 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
PFW
Formula
C31 H30 N4 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

PFW in 1 structure; the first of them:

  • 3QPP · Structure of PDE10-inhibitor complex · PFW A999 · binds LEU625, PHE629, LEU665, SER667, VAL668, ILE682, TYR683, PHE686 and 11 more

Residues it binds most

PHE 1, VAL 1, GLY 1, LEU 1, ALA 1, GLN 1, GLU 1, ILE 1, LYS 1, MET 1 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide

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