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Ligand · PFR

PFR · 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline

PFR, 7-methoxy-4-[(3S)-3-phenylpiperidin-1-yl]-6-[2-(pyridin-2-yl)ethoxy]quinazoline (C27 H28 N4 O2, 440.5 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å…

Component
PFR
Formula
C27 H28 N4 O2
Class
ligand
Structures
1
PDB entries
1

Binding sites

PFR in 1 structure; the first of them:

  • 3QPO · Structure of PDE10-inhibitor complex · PFR A999 · binds LEU625, PHE629, LEU665, SER667, VAL668, ILE682, TYR683, PHE686 and 10 more

Residues it binds most

PHE 1, VAL 1, GLY 1, LEU 1, ALA 1, GLN 1, GLU 1, ILE 1, MET 1, PRO 1 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion

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