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Ligand · PFI

PFI · (6S)-6-cyclopentyl-6-[2-(3-fluoro-4-isopropoxyphenyl)ethyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one

PFI, (6S)-6-cyclopentyl-6-[2-(3-fluoro-4-isopropoxyphenyl)ethyl]-4-hydroxy-5,6-dihydro-2H-pyran-2-one (C21 H27 F O4, 362.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
PFI
Formula
C21 H27 F O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

PFI in 2 structures; the first of them:

  • 2HAI · Crystal structure of HCV NS5B RNA polymerase in complex with novel class of… · PFI A601 · binds LEU419, ARG422, MET423, LEU474, HIS475, SER476, TYR477, ILE482 and 6 more
  • 2HAI · Crystal structure of HCV NS5B RNA polymerase in complex with novel class of… · PFI A601 · binds LEU419, ARG422, MET423, LEU474, HIS475, SER476, TYR477, ILE482 and 6 more

Residues it binds most

LEU 2, ARG 2, ALA 2, HIS 2, ILE 2, MET 2, SER 2, TRP 2, TYR 2, VAL 2 (residue and the binding sites it lines).

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