GL1X · GenesisL1 explorer

Ligand · PF9

PF9 · 2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline

PF9, 2-{[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline (C25 H20 N4 O, 392.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the…

Component
PF9
Formula
C25 H20 N4 O
Class
ligand
Structures
3
PDB entries
2

Binding sites

PF9 in 3 structures; the first of them:

  • 3HR1 · Discovery of novel inhibitors of PDE10A · PF9 A999 · binds TYR514, LEU625, LEU665, SER667, VAL668, THR678, ILE682, TYR683 and 9 more
  • 5SJX · CRYSTAL STRUCTURE OF HUMAN PHOSPHODIESTERASE 10 IN COMPLEX WITH… · PF9 A804 · binds TYR524, LEU635, ASP674, LEU675, SER677, VAL678, THR688, ALA689 and 11 more
  • 3HR1 · Discovery of novel inhibitors of PDE10A · PF9 A999 · binds TYR514, LEU625, LEU665, SER667, VAL668, THR678, ILE682, TYR683 and 9 more

Residues it binds most

LEU 6, PHE 6, TYR 6, VAL 6, GLN 6, GLU 6, GLY 6, ILE 6, LYS 6, MET 6 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.