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Ligand · PF8

PF8 · 2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline

PF8, 2-{[4-(4-pyridin-4-yl-1H-pyrazol-3-yl)phenoxy]methyl}quinoline (C24 H18 N4 O, 378.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it…

Component
PF8
Formula
C24 H18 N4 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

PF8 in 2 structures; the first of them:

  • 3HQZ · Discovery of novel inhibitors of PDE10A · PF8 A999 · binds TYR514, LEU625, LEU665, SER667, VAL668, THR678, ILE682, TYR683 and 9 more
  • 3HQZ · Discovery of novel inhibitors of PDE10A · PF8 A999 · binds TYR514, LEU625, LEU665, SER667, VAL668, THR678, ILE682, TYR683 and 9 more

Residues it binds most

LEU 2, PHE 2, TYR 2, VAL 2, GLN 2, GLU 2, GLY 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • SO4 · Sulfate ion

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