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Ligand · PD4

PD4 · 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one

PD4, 6-(6-methoxypyridin-3-yl)-2-[(2-morpholin-4-ylethyl)amino]-4-(2-propoxyethyl)pyrido[2,3-b]pyrazin-3(4H)-one (C24 H32 N6 O4, 468.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
PD4
Formula
C24 H32 N6 O4
Class
ligand
Structures
2
PDB entries
1

Binding sites

PD4 in 2 structures; the first of them:

  • 3HC8 · Investigation of Aminopyridiopyrazi s as PDE5 Inhibitors: Evaluation of Modifications to… · PD4 A901 · binds TYR612, LEU725, ALA726, ILE729, LEU765, ALA767, ILE768, GLN775 and 10 more
  • 3HC8 · Investigation of aminopyridiopyrazinones as PDE5 inhibitors: evaluation of modifications… · PD4 A901 · binds TYR612, LEU725, ALA726, ILE729, LEU765, ALA767, ILE768, GLN775 and 10 more

Residues it binds most

ALA 2, ILE 2, LEU 2, GLN 2, PHE 2, MET 2, TYR 2, VAL 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

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