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Ligand · PCY

PCY · Pactamycin

PCY, Pactamycin (C28 H38 N4 O8, 558.6 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (5 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
PCY
Formula
C28 H38 N4 O8
Class
ligand
Structures
7
PDB entries
5

Binding sites

PCY in 7 structures; the first of them:

  • 1HNX · Structure of the thermus thermophilus 30S ribosomal subunit in complex with pactamycin · PCY A1632 · binds U692, G693, A694, A787, U788, U789, C795, C796 and 4 more
  • 4KHP · Structure of the Thermus thermophilus 30S ribosomal subunit in complex with… · PCY A1608 · binds U676, G677, A678, A771, U772, U773, C779, C780 and 5 more
  • 4U4Y · Crystal structure of Pactamycin bound to the yeast 80S ribosome · PCY 22178 · binds U903, G904, A905, A998, U999, C1000, C1006, C1007 and 2 more
  • 4W2G · Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin… · PCY AA3231 · binds U692, G693, A694, A787, U788, U789, C795, C796 and 5 more
  • 4W2H · Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin… · PCY AA3191 · binds U692, G693, A694, A787, U788, U789, C795, C796 and 5 more
  • 1HNX · Structure of the thermus thermophilus 30S ribosomal subunit in complex with pactamycin · PCY A1632 · binds U692, G693, A694, A787, U788, U789, C795, C796 and 4 more
  • 4KHP · Structure of the thermus thermophilus 30S ribosomal subunit in complex with… · PCY A1608 · binds U676, G677, A678, A771, U772, U773, C779, C780 and 5 more

Residues it binds most

U 10, A 10, C 10, G 10, GLY 8, ARG 2, LEU 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion
  • PAR · Paromomycin
  • SF4 · Iron/sulfur cluster
  • K · Potassium ion
  • OHX · osmium (III) hexammine

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