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Ligand · PB9

PB9 · methyl 4-{[{(3S)-6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}(pyridin-2-ylsulfonyl)amino]methyl}piperidine-1-carboxylate

PB9, methyl 4-{[{(3S)-6-cyano-1-[(1-methyl-1H-imidazol-5-yl)methyl]-1,2,3,4-tetrahydroquinolin-3-yl}(pyridin-2-ylsulfonyl)amino]methyl}piperidine-1-carboxylate (C28 H33 N7 O4 S, 563.7 g/mol), in the MolNFT structures on GenesisL1: bound in…

Component
PB9
Formula
C28 H33 N7 O4 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

PB9 in 2 structures; the first of them:

  • 2R2L · Structure of Farnesyl Protein Transferase bound to PB-93 · PB9 B425 · binds TYR131, TYR93, LEU96, ALA98, SER99, TRP102, LEU103, TRP106 and 11 more
  • 2R2L · Structure of farnesyl protein transferase bound to pb-93 · PB9 B425 · binds TYR131, TYR93, LEU96, ALA98, SER99, TRP102, LEU103, TRP106 and 11 more

Residues it binds most

TYR 2, ALA 2, ASP 2, HIS 2, LEU 2, TRP 2, ARG 2, CYS 2, PHE 2, PRO 2 (residue and the binding sites it lines).

Found with

  • FPP · Farnesyl diphosphate
  • ZN · Zinc ion

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