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Ligand · P5A

P5A · 5'-O-(N-(L-prolyl)-sulfamoyl)adenosine

P5A, 5'-O-(N-(L-prolyl)-sulfamoyl)adenosine (C15 H21 N7 O7 S, 443.4 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
P5A
Formula
C15 H21 N7 O7 S
Class
ligand
Structures
5
PDB entries
4

Binding sites

P5A in 5 structures; the first of them:

  • 1H4S · Prolyl-tRNA synthetase from Thermus thermophilus complexed with tRNApro(CGG) and a… · P5A A1478 · binds THR111, GLU113, ARG142, GLU144, PHE150, LEU151, ARG152, THR153 and 16 more
  • 1NJ5 · Crystal structure of Prolyl-tRNA Synthetase from Methanothermobacter thermautotrophicus… · P5A A510 · binds THR117, GLU119, ARG148, GLU150, ILE158, ARG159, VAL160, ILE163 and 15 more
  • 2I4M · Rhodopseudomonas palustris prolyl-tRNA synthetase in complex with ProAMS · P5A B439 · binds THR109, GLU111, ARG140, VAL149, MET150, GLY152, PHE155, MET157 and 14 more
  • 2J3L · Prolyl-tRNA synthetase from Enterococcus faecalis complexed with a prolyl-adenylate… · P5A A1576 · binds THR109, GLU111, ARG140, GLU142, LEU149, LEU150, ARG151, GLY152 and 16 more
  • 1NJ5 · Crystal structure of prolyl-tRNA synthetase from methanothermobacter thermautotrophicus… · P5A A510 · binds THR117, GLU119, ARG148, GLU150, ILE158, ARG159, VAL160, ILE163 and 15 more

Residues it binds most

GLY 8, ARG 8, GLU 8, PHE 8, THR 8, ILE 5, HIS 6, LEU 6, TYR 6, MET 4 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • MG · Magnesium ion
  • SO4 · Sulfate ion

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