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Ligand · P37

P37 · N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide

P37, N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide (C24 H21 F2 N5 O2, 449.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry).…

Component
P37
Formula
C24 H21 F2 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

P37 in 2 structures; the first of them:

  • 3GFE · Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a… · P37 A361 · binds VAL38, ALA51, VAL52, LYS53, GLU71, LEU74, LEU75, ILE84 and 13 more
  • 3GFE · Crystal structure of P38A mitogen-activated protein kinase in complex with a… · P37 A361 · binds VAL38, ALA51, VAL52, LYS53, GLU71, LEU74, LEU75, ILE84 and 13 more

Residues it binds most

LEU 2, ALA 2, ASP 2, VAL 2, GLU 2, GLY 2, HIS 2, ILE 2, LYS 2, MET 2 (residue and the binding sites it lines).

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