Ligand · P31
P31 · 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine
P31, 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine (C20 H15 Cl F3 N5, 417.8 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding…
- Component
- P31
- Formula
- C20 H15 Cl F3 N5
- Class
- ligand
- Structures
- 4
- PDB entries
- 2
Binding sites
P31 in 4 structures; the first of them:
- 4R7H · Crystal structure of FMS KINASE domain with a small molecular inhibitor, PLX3397 · P31 A1001 · binds VAL548, ARG549, TRP550, LEU588, VAL596, ALA614, LYS616, SER632 and 13 more
- 7KHG · Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397 · P31 A1001 · binds TRP557, LEU595, VAL603, ALA621, LYS623, GLU640, LEU644, LEU647 and 14 more
- 4R7H · Crystal structure of fms kinase domain with a small molecular inhibitor, PLX3397 · P31 A1001 · binds VAL548, ARG549, TRP550, LEU588, VAL596, ALA614, LYS616, SER632 and 13 more
- 7KHG · Crystal structure of kit kinase domain with a small molecule inhibitor, PLX3397 · P31 A1001 · binds TRP557, LEU595, VAL603, ALA621, LYS623, GLU640, LEU644, LEU647 and 14 more
Residues it binds most
LEU 4, VAL 4, GLU 4, CYS 4, GLY 4, ILE 4, ALA 4, ASP 4, LYS 4, PHE 4 (residue and the binding sites it lines).
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.