GL1X · GenesisL1 explorer

Ligand · P30

P30 · 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea

P30, 1-(5-tert-butyl-1,2-oxazol-3-yl)-3-(4-{7-[2-(morpholin-4-yl)ethoxy]imidazo[2,1-b][1,3]benzothiazol-2-yl}phenyl)urea (C29 H32 N6 O4 S, 560.7 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every…

Component
P30
Formula
C29 H32 N6 O4 S
Class
ligand
Structures
4
PDB entries
2

Binding sites

P30 in 4 structures; the first of them:

  • 4RT7 · Crystal Structure of FLT3 with a small molecule inhibitor · P30 A1001 · binds LYS614, LEU616, VAL624, ALA642, LYS644, GLU661, MET665, LEU668 and 14 more
  • 4XUF · Crystal structure of the FLT3 kinase domain bound to the inhibitor quizartinib (AC220) · P30 A1001 · binds LEU616, VAL624, ALA642, LYS644, GLU661, MET664, MET665, ILE674 and 16 more
  • 4RT7 · Crystal structure of FLT3 with a small molecule inhibitor · P30 A1001 · binds LYS614, LEU616, VAL624, ALA642, LYS644, GLU661, MET665, LEU668 and 14 more
  • 4XUF · Crystal structure of the FLT3 kinase domain bound to the inhibitor quizartinib (AC220) · P30 A1001 · binds LEU616, VAL624, ALA642, LYS644, GLU661, MET664, MET665, ILE674 and 16 more

Residues it binds most

LEU 6, CYS 6, PHE 6, TYR 6, VAL 6, ALA 6, ILE 6, MET 6, GLU 6, LYS 6 (residue and the binding sites it lines).

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.