Ligand · P02
P02 · N'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-N-ethyl-N-methylsulfuric diamide
P02, N'-{3-[5-(2-aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl}-N-ethyl-N-methylsulfuric diamide (C20 H25 F N6 O2 S2, 464.6 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding…
- Component
- P02
- Formula
- C20 H25 F N6 O2 S2
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
P02 in 2 structures; the first of them:
- 4XV3 · B-Raf Kinase V600E oncogenic mutant in complex with PLX7922 · P02 A801 · binds SER465, VAL471, ALA481, LYS483, LEU505, LEU514, PHE516, ILE527 and 11 more
- 4XV3 · B-RAF kinase V600E oncogenic mutant in complex with PLX7922 · P02 A801 · binds SER465, VAL471, ALA481, LYS483, LEU505, LEU514, PHE516, ILE527 and 11 more
Residues it binds most
PHE 2, ASN 2, GLY 2, LEU 2, ALA 2, ASP 2, CYS 2, GLN 2, ILE 2, LYS 2 (residue and the binding sites it lines).
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.