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Ligand · OZ1

OZ1 · 4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide

OZ1, 4-amino-N-[(2,4-difluorophenyl)methyl]-1-hydroxy-6-(6-hydroxyhexyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide (C22 H24 F2 N4 O4, 446.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (2 PDB entries). Every…

Component
OZ1
Formula
C22 H24 F2 N4 O4
Class
ligand
Structures
2
PDB entries
2

Binding sites

OZ1 in 2 structures; the first of them:

  • 8FNQ · Structure of E138K/G140A/Q148K HIV-1 intasome with 4d bound · OZ1 A301 · binds ASP64, CYS65, ASP116, ASN117, GLY118, PRO142, TYR143, PRO145 and 6 more
  • 6PUY · Structure of HIV cleaved synaptic complex (csc) intasome bound with magnesium and insti… · OZ1 A304 · binds ASP64, ASP116, ASN117, PRO142, TYR143, PRO145, GLN146, GLU152 and 3 more

Residues it binds most

ASP 3, PRO 3, ASN 3, DA 3, DC 3, DG 3, GLN 3, GLU 3, TYR 3, CYS 2 (residue and the binding sites it lines).

Found with

  • MG · Magnesium ion
  • ZN · Zinc ion

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