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Ligand · OWG

OWG · 3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-6,7-dimethoxy-1-(4-methoxyphenyl)-3,4-dihydrophthalazin-2(1H)-yl]propan-1-one

OWG, 3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-6,7-dimethoxy-1-(4-methoxyphenyl)-3,4-dihydrophthalazin-2(1H)-yl]propan-1-one (C33 H38 N6 O6, 614.7 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record…

Component
OWG
Formula
C33 H38 N6 O6
Class
ligand
Structures
1
PDB entries
1

Binding sites

OWG in 1 structure; the first of them:

  • 6PRD · S. aureus dihydrofolate reductase co-crystallized with para… · OWG A403 · binds LEU5, VAL6, ALA7, LEU20, PRO25, ASP27, LEU28, LYS29 and 10 more

Residues it binds most

LEU 1, LYS 1, PRO 1, VAL 1, ALA 1, ARG 1, ASN 1, ASP 1, ILE 1, PHE 1 (residue and the binding sites it lines).

Found with

  • NAP · Nadp nicotinamide-adenine-dinucleotide phosphate
  • GOL · Glycerol

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