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Ligand · OVI

OVI · 2-(4-{[2-(2,6-difluorophenyl)-5-oxo-5H-pyrrolo[3,4-d]pyrimidin-4-yl]amino}phenyl)-N-ethylacetamide

OVI, 2-(4-{[2-(2,6-difluorophenyl)-5-oxo-5H-pyrrolo[3,4-d]pyrimidin-4-yl]amino}phenyl)-N-ethylacetamide (C22 H17 F2 N5 O2, 421.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its…

Component
OVI
Formula
C22 H17 F2 N5 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

OVI in 2 structures; the first of them:

  • 7UYR · Crystal structure of TYK2 kinase domain in complex with compound 12 · OVI A1201 · binds ARG901, ASP902, LEU903, GLY904, GLU905, GLY906, VAL911, ALA928 and 14 more
  • 7UYR · Crystal structure of TYK2 kinase domain in complex with compound 12 · OVI A1201 · binds ARG901, ASP902, LEU903, GLY904, GLU905, VAL911, ALA928, GLU979 and 10 more

Residues it binds most

GLY 2, ASP 2, LEU 2, ARG 2, GLU 2, VAL 2, ALA 2, ASN 2, PRO 2, TYR 2 (residue and the binding sites it lines).

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