GL1X · GenesisL1 explorer

Ligand · OT5

OT5 · 1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone

OT5, 1-[6-(3,5-dichloro-4-hydroxyphenyl)-4-({trans-4-[(dimethylamino)methyl]cyclohexyl}amino)-1,5-naphthyridin-3-yl]ethanone (C25 H28 Cl2 N4 O2, 487.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
OT5
Formula
C25 H28 Cl2 N4 O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

OT5 in 2 structures; the first of them:

  • 4CQG · The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative MELK… · OT5 A1332 · binds ILE17, GLY18, THR19, GLY20, VAL25, ALA38, LYS40, GLU57 and 13 more
  • 4CQG · The crystal structure of MPK38 in complex with OTSSP167, an orally- administrative melk… · OT5 A1332 · binds ILE17, GLY18, THR19, GLY20, VAL25, ALA38, LYS40, GLU57 and 13 more

Residues it binds most

GLU 2, GLY 2, LEU 2, CYS 2, ILE 2, ALA 2, ASN 2, ASP 2, LYS 2, THR 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.