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Ligand · OPW

OPW · ~{N}-[5-(5-methoxy-1,3-benzothiazol-2-yl)pyridin-3-yl]ethanamide

OPW, ~{N}-[5-(5-methoxy-1,3-benzothiazol-2-yl)pyridin-3-yl]ethanamide (C15 H13 N3 O2 S, 299.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues…

Component
OPW
Formula
C15 H13 N3 O2 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

OPW in 2 structures; the first of them:

  • 6YF8 · DYRK1A with PST001 · OPW A501 · binds ILE165, LYS167, PHE170, VAL173, ALA186, LYS188, GLU203, VAL222 and 9 more
  • 6YF8 · DYRK1A with PST001 · OPW A501 · binds ILE165, PHE170, VAL173, ALA186, LYS188, PHE238, GLU239, MET240 and 4 more

Residues it binds most

VAL 8, LEU 8, PHE 8, GLU 8, LYS 8, ALA 8, ASP 8, MET 8, ASN 7, ILE 6 (residue and the binding sites it lines).

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