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Ligand · OOZ

OOZ · (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S}, 23~{S},24~{R},25~{S},27~{R})-17-ethyl-25-methoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1, 14,23-tris(oxidanyl)-11,28-dioxa-4-azatricyclo[22.3.1.0^{4,9}]octacos-18-ene-2,3,10,16-tetrone

OOZ, (1~{R},9~{S},12~{S},13~{R},14~{S},17~{R},18~{E},21~{S}, 23~{S},24~{R},25~{S},27~{R})-17-ethyl-25-methoxy-12-[(~{E})-1-[(1~{R},3~{R},4~{R})-3-methoxy-4-oxidanyl-cyclohexyl]prop-1-en-2-yl]-13,19,21,27-tetramethyl-1…

Component
OOZ
Formula
C42 H67 N O12
Class
ligand
Structures
2
PDB entries
1

Binding sites

OOZ in 2 structures; the first of them:

  • 6YF3 · FKBP12 in complex with the BMP potentiator compound 10 at 1.00A resolution · OOZ A201 · binds TYR26, PHE36, ASP37, ARG42, PHE46, GLU54, VAL55, ILE56 and 7 more
  • 6YF3 · FKBP12 in complex with the bmp potentiator compound 10 at 1.00A resolution · OOZ A201 · binds TYR26, PHE36, ASP37, ARG42, PHE46, GLU54, VAL55, ILE56 and 6 more

Residues it binds most

PHE 2, ILE 2, TYR 2, ALA 2, ARG 2, ASP 2, GLU 2, HIS 2, TRP 2, VAL 2 (residue and the binding sites it lines).

Found with

  • CD · Cadmium ion
  • NA · Sodium ion
  • CL · Chloride ion

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