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Ligand · OLP

OLP · 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine

OLP, 2-(2-hydroxyethylamino)-6-(3-chloroanilino)-9-isopropylpurine (C16 H19 Cl N6 O, 346.8 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
OLP
Formula
C16 H19 Cl N6 O
Class
ligand
Structures
4
PDB entries
2

Binding sites

OLP in 4 structures; the first of them:

  • 2CMW · Structure of Human Casein kinase 1 gamma-1 in complex with 2-(2… · OLP A1340 · binds ILE50, GLY51, LEU58, ALA71, TYR91, PRO102, LEU118, GLU119 and 9 more
  • 3BPR · Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER… · OLP A900 · binds LEU593, VAL601, ALA617, LYS619, ILE650, LEU671, PRO672, PHE673 and 7 more
  • 2CMW · Structure of human casein kinase 1 gamma-1 in complex with 2-(2… · OLP A1340 · binds ILE50, GLY51, LEU58, ALA71, TYR91, PRO102, LEU118, GLU119 and 9 more
  • 3BPR · Crystal structure of catalytic domain of the proto-oncogene tyrosine- protein kinase mer… · OLP A900 · binds LEU593, VAL601, ALA617, LYS619, ILE650, LEU671, PRO672, PHE673 and 7 more

Residues it binds most

LEU 14, ALA 12, LYS 12, TYR 14, GLY 12, MET 8, PRO 10, VAL 12, ILE 12, ASP 8 (residue and the binding sites it lines).

Found with

  • NA · Sodium ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • ACT · Acetate ion

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