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Ligand · OK5

OK5 · (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-[[2-(2-methoxyphenyl)pyrimidin-4-yl]methoxy]phenyl]propanoic acid

OK5, (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-[2-[[2-(2-methoxyphenyl)pyrimidin-4-yl]methoxy]phenyl]propanoic acid (C47 H44 Cl F N6 O6 S, 875.4…

Component
OK5
Formula
C47 H44 Cl F N6 O6 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

OK5 in 3 structures; the first of them:

  • 6YBL · Structure of MBP-Mcl-1 in complex with compound 9m · OK5 A402 · binds VAL216, VAL220, HIS224, ALA227, PHE228, GLY230, MET231, LEU235 and 12 more
  • 8EKX · Structure of MBP-Mcl-1 in complex with MIK665 · OK5 A4000 · binds VAL216, VAL220, HIS224, ALA227, PHE228, GLY230, MET231, LEU235 and 11 more
  • 6YBL · Structure of mbp-mcl-1 in complex with compound 9M · OK5 A402 · binds VAL216, VAL220, HIS224, ALA227, PHE228, GLY230, MET231, LEU235 and 11 more

Residues it binds most

PHE 3, VAL 3, LEU 3, GLY 3, MET 3, ALA 3, ARG 3, HIS 3, THR 3, ASN 1 (residue and the binding sites it lines).

Found with

  • GLC · alpha-D-glucopyranose

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