Ligand · OJT

OJT · (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(3-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-(2-methoxyphenyl)propanoic acid

OJT, (2~{R})-2-[5-[3-chloranyl-2-methyl-4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-6-(3-chlorophenyl)thieno[2,3-d]pyrimidin-4-yl]oxy-3-(2-methoxyphenyl)propanoic acid (C36 H36 Cl2 N4 O5 S, 707.7 g/mol), in the MolNFT structures on…

Component: OJT
Formula: C36 H36 Cl2 N4 O5 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

OJT in 2 structures; the first of them:

6YBG · Structure of Mcl-1 in complex with compound 2g · OJT A401 · binds HIS224, ALA227, PHE228, GLY230, MET231, LYS234, LEU235, LEU246 and 8 more
6YBG · Structure of mcl-1 in complex with compound 2G · OJT A401 · binds HIS224, ALA227, PHE228, GLY230, MET231, LYS234, LEU235, LEU246 and 8 more

Residues it binds most

LEU 4, PHE 4, MET 4, VAL 4, ARG 4, ALA 4, GLY 4, HIS 4, THR 4, GLU 2 (residue and the binding sites it lines).

Found with

CL · Chloride ion

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