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Ligand · OHN

OHN · N-3-oxo-dodecanoyl-L-homoserine lactone

OHN, N-3-oxo-dodecanoyl-L-homoserine lactone (C16 H27 N O4, 297.4 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
OHN
Formula
C16 H27 N O4
Class
ligand
Structures
5
PDB entries
4

Binding sites

OHN in 5 structures; the first of them:

  • 6N9R · Structure of the Quorum Quenching lactonase from Parageobacillus caldoxylosilyticus bound… · OHN A303 · binds MET20, MET22, TRP26, PHE48, MET86, PHE87, HIS120, LEU121 and 10 more
  • 8EY1 · Structure of Arabidopsis fatty acid amide hydrolase mutant S305A in complex with… · OHN D700 · binds LYS205, ASP207, LEU254, GLY255, MET256, GLY257, THR258, SER281 and 14 more
  • 6N9R · Structure of the quorum quenching lactonase from parageobacillus caldoxylosilyticus bound… · OHN A303 · binds MET20, MET22, TRP26, PHE48, MET86, PHE87, HIS120, LEU121 and 10 more
  • 6V7W · Crystal structure of lasr-AQS1 complex from pseudomonas aeruginosa · OHN B301 · binds LEU36, TYR47, ILE52, TYR56, TRP60, ARG61, TYR64, ASP73 and 9 more
  • 6V7X · Structure of a phage-encoded quorum sensing anti-activator, AQS1 bound to lasr · OHN B301 · binds LEU36, TYR47, ILE52, TYR56, TRP60, TYR64, ASP73, THR75 and 10 more

Residues it binds most

GLY 14, ASP 14, MET 11, ILE 14, PHE 13, HIS 6, TYR 9, ALA 14, LEU 10, THR 8 (residue and the binding sites it lines).

Found with

  • CO · Cobalt (II) ion
  • FE · Fe (III) ion
  • SO4 · Sulfate ion
  • 1PE · Pentaethylene glycol
  • ACT · Acetate ion
  • EDO · 1,2-ethanediol
  • PGE · Triethylene glycol

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