Ligand · OFH

OFH · (4R)-4-[(2-chloro-4-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}phenyl)sulfonyl]-N-{1-[(E)-iminomethyl]cyclopropyl}-1-{[1-(trifluoromethyl)cyclopropyl]carbonyl}-L-prolinamide

OFH, (4R)-4-[(2-chloro-4-{[(2S)-1,1,1-trifluoropropan-2-yl]oxy}phenyl)sulfonyl]-N-{1-[(E)-iminomethyl]cyclopropyl}-1-{[1-(trifluoromethyl)cyclopropyl]carbonyl}-L-prolinamide (C23 H24 Cl F6 N3 O5 S, 604.0 g/mol), in the MolNFT structures on…

Component: OFH
Formula: C23 H24 Cl F6 N3 O5 S
Class: ligand
Structures: 2
PDB entries: 1

Binding sites

OFH in 2 structures; the first of them:

4BPV · Mouse cathepsin S with covalent ligand · OFH A1341 · binds GLN141, GLY145, ALA146, CYS147, TRP148, LYS187, GLY190, GLY191 and 10 more
4BPV · Mouse cathepsin S with covalent ligand · OFH A1341 · binds GLN141, GLY145, ALA146, CYS147, TRP148, LYS187, GLY190, GLY191 and 10 more

Residues it binds most

GLY 10, TYR 10, HIS 10, ALA 10, ASN 10, CYS 10, GLN 10, LYS 10, MET 10, TRP 10 (residue and the binding sites it lines).

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