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Ligand · OFG

OFG · 3-[(1R)-1-[5-fluoranyl-2-(1,2,3-triazol-2-yl)phenyl]ethoxy]-5-(3-methyl-1H-pyrazol-4-yl)pyridin-2-amine

OFG, 3-[(1R)-1-[5-fluoranyl-2-(1,2,3-triazol-2-yl)phenyl]ethoxy]-5-(3-methyl-1H-pyrazol-4-yl)pyridin-2-amine (C19 H18 F N7 O, 379.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with…

Component
OFG
Formula
C19 H18 F N7 O
Class
ligand
Structures
2
PDB entries
1

Binding sites

OFG in 2 structures; the first of them:

  • 4CCB · Structure of the Human Anaplastic Lymphoma Kinase in Complex with… · OFG A2401 · binds LEU1122, GLY1123, HIS1124, VAL1130, ALA1148, LYS1150, VAL1180, LEU1196 and 12 more
  • 4CCB · Structure of the human anaplastic lymphoma kinase in complex with 3… · OFG A2401 · binds LEU1122, GLY1123, HIS1124, VAL1130, ALA1148, LYS1150, VAL1180, LEU1196 and 12 more

Residues it binds most

LEU 2, GLY 2, ALA 2, ASP 2, VAL 2, ARG 2, ASN 2, CYS 2, GLU 2, HIS 2 (residue and the binding sites it lines).

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