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Ligand · OCR

OCR · (5E,8E,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid

OCR, (5E,8E,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic acid (C20 H30 O3, 318.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
OCR
Formula
C20 H30 O3
Class
ligand
Structures
4
PDB entries
2

Binding sites

OCR in 4 structures; the first of them:

  • 2ZK4 · Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed… · OCR A1 · binds PHE264, ILE267, ILE281, GLY284, CYS285, ARG288, SER289, ALA292 and 10 more
  • 3ADW · Human PPARgamma ligand-binding domain in complex with 5-methoxy-indole acetate and… · OCR A1 · binds PHE226, LEU228, LEU255, PHE264, ILE267, THR268, ARG280, ILE281 and 13 more
  • 2ZK4 · Human peroxisome proliferator-activated receptor gamma ligand binding domain complexed… · OCR A1 · binds PHE264, ILE267, ILE281, GLY284, CYS285, ARG288, SER289, ALA292 and 10 more
  • 3ADW · Human ppargamma ligand-binding domain in complex with 5-methoxy-indole acetate and… · OCR A1 · binds PHE226, LEU228, LEU255, PHE264, ILE267, THR268, ARG280, ILE281 and 13 more

Residues it binds most

ILE 8, LEU 8, MET 8, SER 8, ARG 8, PHE 6, ALA 8, CYS 8, GLY 8, GLU 6 (residue and the binding sites it lines).

Found with

  • MYI · (5-methoxy-1H-indol-3-yl)acetic acid

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